Pharmaceutical Raw Nootropic Smart Drugs Powder Picamilon Sodium for Sleeping Well CAS 62936-56-5

Specification
Purity: ≥98%
Molecular Weight: 230.20 g/mol
Melting Point: 208.0-212.0°C
Molecular Formula: C10H11N2O3 •Na
Synonyms: Picamilon, Pikamilone sodium salt, Pikamilone, Pikamilon sodium salt, Nicotinoyl-GABA sodium salt, 4-(Pyridine-3-carbonylamino)butanoic acid sodium salt, Monosodium 4-(pyridine-3-carbonylamino)butanoate, Monosodium 4-Nicotinoylaminobutyrate, N-(3-Pyridinylcarbonyl)-4-aminobutyric acid sodium
PubChem CID: 23663986
SMILES: C1=CC(=CN=C1)C(=O)NCCCC(=O)[O-].[Na+]

Picamilon is a dietary supplement and nootropic drug. It is a combination of Vitamin B3, also known as niacin, and the neurotransmitter GABA. This supplement is taken orally, typically in powder or tablet form, and is able to cross the blood-brain barrier. Once in the brain, it is hydrolyzed into GABA and niacin.

The function of picamilon is two-fold, since, when the compound is broken down into its constituent parts in the brain, each one has a different effect. Niacin acts as a vasodilator, which enlarges the blood vessels of the brain. This, in turn, leads to increased blood flow, reduced blood pressure, and is thought to assist in the management of migraine headache pain.

When the second part of the picamilon compound, GABA, is activated in the brain, it is a believed to create a moderate anti-anxiety effect. This is known as an anxiolytic response, and is due to that fact that GABA is an inhibitory neurotransmitter. GABA limits, rather than encourages, certain brain functions.

Picamilon Benefits:
The primary Nootropic benefits of Picamilon center on mood boosting and overall brain function improvements. This includes helping to reduce feelings of stress and anxiety.

In fact, many users feel that Picamilon is so good at reducing these feelings that they use Picamilon on a regular basis to help relax. An improved positive outlook and attitude will also often follow. Once a person is relaxed, they will usually find themselves having improved sleep which is also more restful and deeper.

As a brain booster, Picamilon benefits also include better mental energy and improved clarity and focus. It is easier to think and make decisions as well when using Picamilon supplements.

There are also a number of additional health benefits associated with daily dosages of Picamilon nootropic. For starters, Picamilon helps to reduce and regulate blood pressure in the body. There is also a lot of evidence demonstrating that it can alleviate migraines and poor cerebral blood flow and circulation.

This supplement has further been shown to treat the symptoms of acute alcohol intoxication and the effects upon the brain. There is even the possibility that Picamilon may act as an anti-oxidant and rid the brain of toxins and other harmful substances.

How Picamilon Works:
It is helpful to think of Picamilon as a mixture of two different chemicals – GABA and Niacin.

Once it is absorbed into the bloodstream both compounds cross over the blood-brain barrier together. This is courtesy of the Niacin pathways since GABA is not capable of this action by itself.

As the GABA enters into the central nervous system it targets receptor sites and performs its job as the chief inhibitory neurotransmitter within the human body. GABA is known to prevent over-stimulation and excitotoxicity of your brain cells which can occur when your neurons are firing faster than they should be.

We experience this over-activity as anxiety and the feeling like you cannot stop thinking about certain memories or future possibilities. Picamilon essentially curbs these excessive thought processes, resulting in a sensation of peace and calm.

Many people are tempted to think of the Niacin found in Picamilon powder simply as a GABA transport method. They would be incorrect; the Niacin from Picamilon is itself active and has a positive nootropic effect on mental performance. This substance is primarily responsible for opening up (or dilating) blood vessels within the brain.

As these passageways open, this leads to the improvement in cerebral blood flow, oxygen supply and glucose metabolism. The result is better cellular energy and improved resource supply to maintain the health of your neurons.

It also helps to keep skin healthy and may even play a role in improving vision in those suffering from glaucoma.

Dosage:
Though picamilon is generally considered to be well-tolerated and mainly without serious side-effects, it is a very potent supplement and should be used responsibly. As with all supplements, it is wise to start with the lowest possible effective dosage and increase gradually as needed.

Recommendations for daily dosage vary considerably, depending to a large extent on the particular effects that you hope to experience. A cumulative dosage of between 50 and 400 mg per day is typical, with most users finding efficacy somewhere between 100 and 200 mg split over two to three doses. However for those who are primarily interested in picamilon’s cognitive enhancements and general mood stabilization lower dosages may prove to be best, while those seeking substantial increases in energy levels may wish to build to higher dosages.

Picamilon works relatively quickly and is fairly long-lasting. Users say effects are generally noticeable within an hour of ingestion and last for 4 to 6 hours. It is water-soluble and can be taken in either capsule or powder form, preferably on an empty stomach.

While some users prefer to cycle picamilon with other nootropics that have an anti-anxiety component, there is no evidence that taking it on a daily basis has any adverse effect.

Stacking & Cycling Picamilon:

Many users have found that stacking and cycling their Picamilon dosages can be very effective. It is certainly very safe and it may even help to increase the effects of other Nootropic supplements like the Racetams including Aniracetam and Piracetam. Even herbs like Valerian Root and Kava can be helpful when used in combination.

There are a number of other Nootropics that have similar effects to Picamilon, but might lead to tolerance if used on a daily basis. This means that it might be helpful to include Picamilon as part of a cycle with something like, say, Phenibut.

Start with the safer option (Picamilon) and use on a 3 or 4 day on and 2 day off cycle. For the days off of Picamilon, substitute with the Phenibut.

Picamilon Side Effects

Picamilon is generally very well-tolerated and very safe with no reports of serious side effects ever published. It can even be used on a regular basis and is less likely to cause tolerance or withdrawal in comparison to Phenibut.

Any Picamilon side effects that one is likely to encounter will be very mild. These may include headaches, nervousness, fatigue, and intestinal issues. Most of these are the result of simply taking too much, so reducing the dosage is normally enough to solve these issues.

About US: 

YIHAN INDUSTRIAL Co.,Ltd is a large hight tech chemical enterprise which specialized in fine chemicals, pharmaceutical raw material and intermediates. Our company integrates R&D, producing, operating and marketing into an organic whole.
We are aim to occupy major market share of USA, Canada, UK, Brazil,
Netherlands, Ireland, New Zealand, Austria, Australia, German and worldwide.
Quality is our life! All products produced in Aseptic Laboratory according to GMP standard. Approved the ISO 9001: 2008 and ISO14001: 2004. Besides, we have a complete Q. A. & Q. C. System.

RFQ:

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
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Q3: Do you Accept Sample Order?
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It is Depending on your location,
For small order, please expect 5-7 days by UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7 Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship

Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.