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|Appearance:||White Crystalline Powder||Molecular Formula:||C15H25ClN2O2|
|Molecular Weight:||264.36||Package:||1kg/aluminium Foil Bag Or As Required|
|Assay:||99%min||Advantage:||Reship, High, Purity,good Atfer Service|
Tetracaine (INN, also known as amethocaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
|Test Items||Specification||Test Results|
|Appearance||Fine, white, crystalline, odorless powder||confirm|
|Identification||ABC in Pass||confirm|
|Solubility||Very soluble in water, soluble in Alcohol;
insoluble in Ether and Benzene
|USP Reference standards||USP Tetracaine Hydrochloride RS.
USP Endotoxin RS.
|Melting point||145~150 degree||146.0~147.5 degree|
|Chromatographic purity||In Pass||confirm|
|Related substance||Not more than the reference solution 0.05%||confirm|
|Residue on ignition||≤0.10%||0.05%|
|Loss on Drying||≤ 0.5%||0.19%|
|Conclusion||Confirms USP 32|
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
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|Step 3||We offer the quotation of products and suitable shipping method for reference.|
|Step 4||You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc.|
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What about the payment? Is it secure?
A: Payment can be TT, West Union, Money Gram. As a well-known supplier, thousands of buyers pay as mentioned. It is warmly welcome to visit our company, discuss and deal face to face.
Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Do you have any reshipment policy?
Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money.