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|Product NaLGD4033me:||AICAR Acadesine||Business Type:||Manufacturer Factory|
|CAS No.:||2627-69-2||Delivery:||1-2 Days|
Product Name: Hot Sell SARMS AICAR/Acadesine Cas 2627-69-2
CAS No: 2627-69-2
Molecular Formular: C9H14N4O5
Molecular Weight: 258.2
Appearance: White powder
Chemical Mame: 5-Aminoimidazole-4-carboxamide ribonucleotide
Package size: 1g/5g/10g/100g or as per customers' requirements
AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in.
AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity (AMPK). AICAR is being clinically used to treat and protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct. Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium .The drug was first used in the 1980’s as a method to preserve blood flow to the heart during surgery. Currently,the drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.
AICAR is a cell permeable activator of AMPactivated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
The word SARM stands for “Selective Androgen Receptor Modulator,” and just like the other selective receptor modulators, SARMS can either block, or stimulate, the same nuclear hormone receptors under different conditions. As an additional advantage, SARMS are orally available and require no injections. In spite of being oral compounds, SARMS are not methylated, so they are not liver toxic. Due to the fact that SARMS are very specific to the androgen receptors, they can be extremely useful for safe muscle building. All in all, SARMS have an abundance of qualities. They are highly beneficial to bones, muscle tissues, and sexual function without the conversion of androgens into estrogens seen with steroids or prohormones. Hence, SARMS offer the benefits of anabolic steroids, but they do not cause the side effects commonly associated with AAS. This quality makes them extremely desirable and intriguing to any class of users.
AICAR (AICA-Riboside) strongly inhibits the transcription of PPARα and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).
As mentioned above, SARMS have steroid like results without the many unwanted side effects that AAS can cause. Here are the side effects of Anabolic Steroids (none of which are present with SARMS use).
1. SARMs’ benefits could be extremely convenient to someone who is out of shape and/or overweight, and wants to use performance enhancing drugs (PED).
2. Furthermore, SARMs could be very useful for someone who has taken a long time off from the gym, or who is totally new to androgens, since they are a good starting point
3. SARMS can be used by bodybuilders, gym users, fitness enthusiasts, or athletes either in conjunction with, or as a replacement for, traditional anabolic steroids for the following purposes:
(1) Applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall, infectious hepatitis and epidemic cerebrospinal meningitis.
(2) Applied in healthcare field, it is used in the health products to nourish brain, protect liver and improve sleep quality.
(3) Applied in comestics, it is used to promote skin metabolism and make skin more tender and firm.
10ml Finished Steroid Injection(Accept custom made, welcome test)
|Product Name||Volume||Each ml contains|
|SU-250||10 ml||Testosterone Propionate 30mg, Testosterone Phenylpropionate 60mg, Testosterone Isocaproate 60mg, Testosterone Decanoate 100mg|
|SU-400||10 ml||Testosterone Propionate 48mg, Testosterone Phenylpropionate 96mg, Testosterone Isocaproate 96mg, Testosterone Decanoate 160mg|
|Testosterone mix 325||10 ml||Testosterone Propionate 65mg, Testosterone Phenylpropionate 65mg, Testosterone Cypionate 85mg, Testosterone Decanoate 110mg|
|TE-300||10 ml||Testosterone Enanthate 300mg|
|TE-250||10 ml||Testosterone Enanthate 250mg|
|TC-200||10 ml||Testosterone Cypionate 200mg|
|TP-100||10 ml||Testosterone Propionate 100mg|
|NPP-200||10 ml||Nandrolone Phenyl Propionate 200mg|
|NPP-100||10 ml||Nandrolone Phenyl Propionate 100mg|
|DECA-300 (ND-300)||10 ml||Nandrolone Decanoate 300mg|
|NANDROMIX-300||10 ml||Nandrolone Phenylpropionate 100mg, Nandrolone Decanoate 200mg|
|BOLDEN-300||10 ml||BU 300mg|
|BOLDEN-600||10 ml||BU 600mg|
|TREN-A 75||10 ml||Trenbolone Acetate 75mg|
|TREN-E 100||10 ml||Trenbolone Enanthate 100mg|
|TRENMIX-200||10 ml||Trenbolone Acetate 75mg, Trenbolone Enanthate 125mg|
|DP-100||10 ml||Drostanolone Propionate 100mg|
|MAST-200||10 ml||Drostanolone Propionate 50mg, Drostanolone Enanathate 150mg|
|TrX-100||10 ml||TrenboloneEnanthate Trenbolone Hexahydrobenzyl|
|PRIMO-100||10 ml||Methenolone Enanthate100mg|
|PROVI-50||10 ml||Mesterolone 50mg|
|Blend-500||10 ml||Tren E 250mg
Mast E 250mg
|Blend-375||10 ml||Tren E 125mg
Mast E 125mg
Test E 125mg
|Anadrol-50||10 ml||Anadrol 50mg|
|WINSTRO-50||10 ml||Stanozolol 50mg|
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