Yihan Industrial Co.,Ltd.

 

Manufacture of Raw Steroids Powder , Finished Liquid , HGH , Peptides and LOCAL ANESTHETIC DRUGS in China .

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Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1

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Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1

China Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1 supplier
Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1 supplier Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1 supplier

Large Image :  Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1

Product Details:

Place of Origin: CHINA
Brand Name: YIHAN
Certification: ISO 9001, USP
Model Number: 936563-96-1

Payment & Shipping Terms:

Minimum Order Quantity: 10 grams
Price: US $8- $14 / grams
Packaging Details: Aluminum foil bag or as your request
Delivery Time: 5-8 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 1000KG per month
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Detailed Product Description
Product Name: Ibrutinib CAS No: 936563-96-1
Purity: 99% Min Transport Packaging: Discreet Packing Ways
Grade: Medicine Grade Sample: Available
Form: White Powder Class: Cancer Treatment Powder
Suitable For: Adult Delivered Time: 2-3 Work Days For Small Quantity
Storage: Shading, Confined Preservation Alias: Ibrutinib POWDER
Business Type: Manufacturer , Factory

High quality Anticancer pharmaceutical active ingredients Ibrutinib powder

 

Quick detail:

 

Name Ibrutinib
CAS 936563-96-1
Appearance white powder
MF C25H24N6O2
MW 440.5
Purity 99%min


 

description:

 

Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.PCI-32765 (Ibrutinib) is a selective and irreversible pyrrolopyrimidine-based inhibitor of BTK with IC50 of 0.5 nM. [1] PCI-32765 binds irreversibly to Cys-481 in BTK and thus is only active with other kinases with such a modifiable cysteine residue. In DOHH2 cells, in which the BCR pathway can be activated by anti-IgG, PCI-32765 inhibits autophosphorylation of BTK (IC50, 11 nM), BTK's physiological substrate, PLCg (IC50, 29 nm), and downstream ERK (IC50, 13 nm).


Ibrutinib is used to treat chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease.

 

 

COA:

 
Items Specifications Results
Appearance White to whitish crystal powder Conforms
Loss on drying NMT 0.5% 0.33%
Residue on ignition NMT 0.1% Conforms
Heavy metal NMT 20ppm Conforms
Assay (HPLC) NLT 99.5% 99.77%
Related substances NMT 0.5% 0.23%
Single impurity NMT 0.1% 0.07%
Conclusion Complies to the Enterprise standard.
 
 

Applications:

 

Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). MCL and CLL are belonged to the B-cell non-Hodgkin's lymphoma, which is difficult to cure and easy to recurrent. Common chemical immunotherapy does not have the targeting, often occurs 3 or 4 adverse reactions. Ibrutinib and B lymphocytes could target with BTK which is necessary for formation, differentiation, and transmission of information, inhibit BTK activity irreversibly, and inhibit tumor cell proliferation and survival effectively. Ibrutinib could be rapidly absorbed after oral administration, during 1~2h reach maximum blood concentration, adverse reactions belong to one or two, therefore, Ibrutinib will become a new choice of treatment of CLL and MCL.

 

 

****Our company introdution:

Yihan Industrial Co., Ltd is a large hight tech chemical enterprise which specialized in steroids powder , semi-finished liquids , peptides , Sarm powder, HGH, HCG, Finished Liquid and other pharmaceutical materials. Our company integrates R&D, producing, operating and marketing into an organic whole.

 


Our advantage:

  • 1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
  • 2. Our company is a professional leading factory in China in pharmaceutical area, We had stable
  • customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries.
  • We can provide good references about our company. As for the quality of the products, We 're sure they can satisfy you well enough;
  • 3. Professional packing with professional materials;
  • 4. Reship Service if being seized by custom.
  • 5. we accept Western Union,Money Gram,Bank Transfer

  
 
FAQ:
 
Q1. Are you a manufacturer?
A: Yes, we have our own factory and lab.

Q2: Is there any discount?
A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.


Q3: How to proceed order?
Let me konw the items, quantity and the destination contruy wihch help me to give you a right price
Please let me know the items you are looking for, quantity and the destination country. After you confirm all details of order, pay money 100% in advance and give us Shipping address. We arrange the shipment at first time after receive payment and offer you the tracking number for your goods, and we will supply after-sales service after you receive parcel.
 
Q4: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

 

Q5: Do you Accept Sample Order?
A: Yes,
For some powder ,we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
For peptides, we accept 10 vials or 1 box.


 
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Anticancer Active Pharmaceutical Ingredients Ibrutinib Powder Cas 936563 96 1

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