Payment & Shipping Terms:
|Useful:||Cance Treatment||Payment:||Wester Union, Paypal, Bank Transfer, Money Gram|
|Shipping Ways:||DHL, HKEMS, EMS (Door To Door)||Name:||Erlotinib Hydrochloride|
anti cancer drugs,
cancer treatment powder
Free Sample Erlotinib hydrochloride / Erlotinib Hcl Api Active Pharmaceutical Ingredient Cas 183319-69-9
Product Name: Erlotinib hydrochloride
Synonyms: ERLOTINIB HCL;ERLOTINIB HCL SALT;ERLOTINIB HCL SALT :TARCEVA;Erlotinib, Hydrochloride Salt;N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva;
Why choose us?
Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company.
We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.
We can do according to the customers' request.
|Make an order||1.Please let me know the items you are looking for, quantity, and the destination country;|
|2.You confirm all details, and offer us purchasing order;|
|3.We send the detail price of our product and offer the suitable shipping method for reference;|
|4.You confirm the order and pay money 100% in advance and send us the detail address.|
|5.We arrange the shipment according to your requirements.|
|6.We offer after-sales service after you receive parcel.|
|Shipping||Provide your addressee info. ( phone number , zip code )|
|Packing||According to different countries and quantity of orders|
|Lead Time||Arranged within 24 hours upon receipt of your payment|
|Photos||Photos of parcel would be offered to tell apart the steroids in advance|
|Delivery Time||Usually 4-6 working days to reach destinations|
|Tracking number||Offered once it is released on the Net .Normally within 24hours upon the receipt of payment.|
|After-sale service||24/7 online for problems and concern related to steroids|
Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
Erlotinib HCl (1 μM) induces apoptosis in DiFi humancolon cancer cells. Erlotinib inhibits growth of a panel of NSCLC cell lines including A549, H322, H3255, H358 H661, H1650, H1975, H1299, H596 with IC50 ranging from 29 nM to >20 μM. Erlotinib HCl(2 μM) significantly inhibits growth of AsPC-1 and BxPC-3 pancreatic cells.
Cells were treated with single dose of erlotinib (1 µM, 24 hours), The greatest cell death was observed in the Txt->OSI-774->media sequence, while the cells treated with the OSI-774->Txt->media sequence resumed proliferation by 72hrs post-treatment. Cleaved PARP and Caspase-3 were detected in the sequence of Txt->OSI-774, and with simultaneous treatment, but not in the sequence of OSI-774->Txt. Further, cleaved PARP and Caspase-3 persisted to 72hrs after the Txt->OSI-774 treatment. These data support the previous results on sub-G1 cells, and molecularly demonstrate an apoptotic response.
Erlotinib had significant dose-dependent efficacy. In the 100mg/kg group there was growth inhibition of 61%. The other groups had the following growth inhibition: 25mg/kg: 46%; 12.5mg/kg: 36%; 6.25mg/kg: 28%. There were no partial or complete regressions.