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|Material:||Steroid Powder||Color:||White Or Yellow|
|Packing:||10g/ Bags, 1kg/box, 5kg/Carton||Useful:||Muscle Gain|
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anti estrogen supplements,
natural anti estrogen
Top Quality Raloxifene Hydrochloride Pharmaceutical Raw Material 82640-04-8 For Bodybuilding
Synonyms:RALOXIFENE HCL;RALOXIFENE HYDROCHLORIDE;ly156758 ;methanone,(6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidin ;KEOXIFENE;KEOXIFENE HYDROCHLORIDE;LY 139481;AKOS 92138
Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family. This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.
The main point of variation between these two agents is their tissue selectivity. While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues, it appears to be estrogenic in bone. This allows it to protect bone density, mimicking the beneficial effects of endogenous estradiol. This is quite different from tamoxifen, which is anti-estrogenic in both breast and bone.
In a role that was novel for an anti-estrogen, raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women. It is also being investigated for several other potential uses, including the treatment and prevention of cardiovascular disease, breast cancer, gynecomastia, prostate cancer, acromegaly, and uterine cancer.
1. Amino acid, nutrient
2. Labeled , intended for use as an internal standard for the quantification by GC- or LC-mass
3. A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.
Mechanism of Action
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors.
This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism). The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors.
1. Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, we had Established long friendly relations of cooperation.
2. Great quality, purity and favourable.
Good quality is one of our secret success, welcome order the samples, MOQ just 10 grams.
3. Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
We have special way could ship 0.01kg to 3.5kg products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.
4. Good after-sales service.