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Pharmaceutical Grade Growth Hormone Peptide Hexarelin CAS 140703-51-1
Molecular formula: C47H58N12O6
MW : 887.04022
CAS number: 140703-51-1
Synonyms: Hexarelin Acetate, HEX, Examorelin
Grade : Pharmaceutical Grade
Appearance White Powder
Storage: Closed, below 2 ~ 8°C preservation
Usage : A synthetic can promote GH release six peptide, clinically used in the treatment of growth hormone secretion deficiency.
Hexarelin Indications: Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the grow factor family which stimulates the release of grow hormone (GH). It can be used medically to treat GH deficiency. Hexarelin is a good all purpose anabolic. Also, since we know that and GH use produces a shutdown of your endogenous levels of those hormones, Hexarelin also seems very useful for "GH-PCT" or "-PCT", as it can help restore your natural levels of those hormones after a cycle of them.
Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems. One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.
Hexarelin is considered to be the strongest peptide stimulating GH secretion. With its use, the increase in cortisol and prolactin levels is also high enough. GHRP-2 is less strong than Hexarelin, but the increase in cortisol and prolactin levels is less too. GHRP-6 is less strong than GHRP-2, but when used in dosage up to 100mcg, it has no influence on the levels of cortisol and prolactin, and in dosage more than 100mcg, the increase in cortisol and prolactin levels is modest
Hexarelin is a peptide structurally similar to GHRP-6, which stimulates secretion of endogenous GH. Hexarelin has the majority of synthetic GH effects, but these effects are less evident with Hexarelin than with GH. The main effects of Hexarelin include increase of strength, growth of new muscle fibers, improving of vessels state, reduction of fat mass. The main difference of Hexarelin from GHRP-6 is that Hexarelin does not promote appetite, because it does not increase the level of ghrelin in the body.
Hexarelin comes in a freeze dried powder just like the other G-HRP peptides and storage should be done in a cool dry place until reconstituted and placed in a refrigerator. Bacteriostatic water is used to reconstitute the powder and an insulin syringe is the preferred method for administering subcutaneous injections of hexarelin. Users will notice 200mcgs is the saturation dose for hexarelin and over a few weeks of use total desensitization may begin to take place. Also, the occasional flare up of the pituitary has been noted when dosing far beyond saturation doses. Desensitization can be cleared easily by taking a break from hexerlin usage for a few days to a few weeks. This G-HRP is the strongest, and because of the desensitization factor, it is believed that the optimal way to use this peptide would be to blend it at low doses with other GHRP's like G-HRP2, G-HRP6 or iPamorelin.
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