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Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder

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Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder

China Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder supplier
Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder supplier Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder supplier Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder supplier

Large Image :  Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder

Product Details:

Place of Origin: CHINA
Brand Name: YIHAN
Certification: USP BP SGS
Model Number: GDF-8

Payment & Shipping Terms:

Minimum Order Quantity: 1 box (10vials )
Price: USD$ 4-10 /vial
Packaging Details: Carton box
Delivery Time: 3-6 working days
Payment Terms: T/T,MoneyGram
Supply Ability: 1000box
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Detailed Product Description
Product: GDF-8 1mg Other Name: GDF8
Specification: 10mg/vial, 10vial/ Box Policy: Reship Policy
Sample: Available Color: Freeze Powder
Specification: According To Customer's Request Grade: Medicine Grade
Form Available1: Peptides Powder
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Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder
 


Quick detail:
 

Product Name GDF 8 Powder ,GDF-8(myostatin)
Brand Name YIHAN
Packing 1box/10vials,1mg/vial
CAS No 901758-09-6
Molecular Formula C221H366N72O67S
Application Pharmaceutical raw materials
purity > 99.0%
 

 

 

Description:

 

 

Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and follistatin-relatedgene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Description:28 kDa protein containing 243 amino acid residues of the human Myostatin Propeptide and 5 additional amino acid residues.

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

 

 

Applications:

1) The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".

2) Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

3) Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer. Myostatin binds to the activin type II receptor, resulting in a recruitment of either coreceptor Alk-3 or Alk-4. This coreceptor then initiates a cell signaling cascade in the muscle, which includes the activation of transcription factors in the SMAD family - SMAD2 and SMAD3. These factors then induce myostatin-specific gene regulation. When applied to myoblasts, myostatin inhibits their differentiation into mature muscle fibers.


Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition[8] Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.

 

 

Myostatin Usage:


A growth factor that regulates the size of muscles beginning in early embryonic development and continuing throughout life. Myostatin acts by inhibiting the growth of muscles, It prevents them from growing too large. Myostatin is also known as growth and differentiation factor 8 (GDF-8)

How does GDF-8 work?
Some studies show that the lack of myostatin gives rise to impressive results in the increase of muscle mass both in humans and in animals. In bones specifically, the lack of myostatin increases its mineral density, resulting in an increase of the calcium levels of the organism. GDF-8 is stored in bones and it is necessary for the correct functionality of the heart, muscles, and nerves as well as for blood clotting.

 
 

COA

 
Appearance White powder Consistent
Purity(HPLC) ≥95% 98.17%
Water <6.0% 4.46%
Acetic Acid 3.0-8.0% 5.60%
Trifluoroacetic Acid <0.25% 0.055%
Peptide ≥80% 84.60%
MS Consistent Consistent


Peptide List:

 

Name Specification
MGF 2mg/vials, 10 vials/box
PEG MGF 2mg/vials, 10 vials/box
CJC-1295 with DAC 2mg/vials, 10 vials/box
CJC-1295 without DAC 2mg/vials, 10 vials/box
PT-141 10mg/vials, 10 vials/box
MT-1 10mg/vials, 10 vials/box
MT-2 10mg/vials, 10 vials/box
GHRP-2 5mg/vials, 10 vials/box
GHRP-2 10mg/vials, 10 vials/box
GHRP-6 5mg/vials, 10 vials/box
GHRP-6 10mg/vials, 10 vials/box
Ipamorelin 2mg/vials, 10 vials/box
Hexarelin 2mg/vials, 10 vials/box
Sermorelin 2mg/vials, 10 vials/box
Oxytocin 2mg/vials, 10 vials/box
TB500 2mg/vials, 10 vials/box
pentadecapeptide BPC 157 2mg/vials, 10 vials/box
HGH 176-191 2mg/vials, 10 vials/box
Triptorelin 2mg/vials, 10 vials/box
Tesamorelin 2mg/vials, 10 vials/box
Gonadorelin 2mg/vials, 10 vials/box
Gonadorelin 10mg/vials, 10 vials/box
DSIP 2mg/vials, 10 vials/box
Selank 5mg/vials, 10 vials/box
ACE 031 1mg/vials,10 vials/box
FOLLISTATIN 315 1mg/vials,10 vials/box
GDF-8 1mg/vials,10 vials/box
FOLLISTATIN 344 1mg/vials,10 vials/box
Epitalon 10mg/vials, 10 vials/box

 

About us:
 
we, Yihan Industrial Co., Ltd from china are specilized in steroids powder , semi-finished liquids , peptides , Sarm powder,HGH,HCG,Finished Liquid and other pharmaceutical materials for many years .
 
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Injectable Growth Hormone Peptides Myostatin Peptide GDF-8 Lyophilized Powder
 
 

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