High Purity Polypeptides Selank 5mg/vial For Anxiety Disorder Treatment
Selank is a pharmacokinetic and anxiolytic drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. Selank is a heptapeptide having the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is a synthetic analogue of human tetrapeptide tufting protein.
Selank is a synthetic analogue of immunomodulatory peptide tufts; therefore, it mimics its many effects. Has been shown to modulate the expression of interleukin-6 (IL-6) and affect the balance of T helper cell cytokines. Has been shown to affect the concentration of monoamine neurotransmitters and induce serotonin metabolism. There is evidence that it may also regulate the expression of brain-derived neurotrophic factor (BDNF) in the brain.
Selank and related peptide drugs have been found to inhibit the degradation of enzymes involved in enkephalin and other endogenous regulatory peptides, and this effect may be involved in its role.
Selank is a synthetic derivative of the human body's naturally produced tetrapeptide Tuftsin. It is a hexapeptide whith a wide range of uses. It was first sinthesized in the late 1990's by the Institute of Molecular Genetics of the Russian Academy of Science. Selank is used as an anxiolytic in the therapy of anxiety and phobic disorders, including generalized anxiety. Its action is similar to that of mild benzodiazepins but without the sedative effects.
Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cell cytokines. It has been shown to influence the concentration of monoamine neurotransmitters and induce metabolism of serotonin. There is evidence that it may also modulate the expression of brain-derived neurotropic factor (BDNF) in rats.
1) improvement of learning and memory processes (reference, reference)
2) increased sensory attention
3) increased curiosity
4) increased mental clarity
5) restoration of balance of serotonergic and noradrenergic brain system activity (reference)
6) anti-anxiety - inhibition of anxiety (reference)
7) antiviral activity with no negative effects (reference)
8) psychostimulant, anti-asthenic - increased mental energy (reference)
9) stabilization of mood and overall feeling of wellbeing
10) reversal of anhedonia (restoring the feeling of pleasure)
11) potential restoration of catecholaminergic system functions after damage due to drug abuse reference
Selank has a low toxicity profile. An overdose of 500 times higher than the normal level has been proven harmless for humans. Large majority of researchers are reporting that it is a “side effect free” compound. Some believe an overdose might cause fatigue.
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