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|Product NaLGD4033me:||SR9011||Business Type:||Manufacturer Factory|
|CAS No.:||1379686-29-9||Delivery:||1-2 Days|
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Healthy Bodybuilding Supplement Sarms SR9009 Stenabolic Steroid Powder SR9011 for Fitness Nutrition
Product Name: SR9011 powder
Other Name: SR 9011/SR-9011
Purity: 98%min by HPLC
CAS No.: 1379686-29-9
Appearance: White powder
M.W.: 479.03524 g/mol
Assay: HPLC; HNRM; LC-MS
SR-9011 is a research drug that was developed by Professor Thomas Burris of Scripps as an agonist of Rev-ErbAα with a half-maximum inhibitory concentration (IC50) = 790 nM for Rev-Erbα and IC50 = 560 nM for Rev-ErbAβ.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic
The new compounds known as SR9011 can increase laboratory metabolism, fat burning and muscle growth.
Scientists at the Scripps Institute (TSRI) have successfully tested a drug called SR9011,
In mice that initiate metabolism and lead to increased muscle development.
In essence, this is a pill of the sport system.
SR9011 changes the metabolic characteristics of skeletal muscle in a similar manner to the observed changes,
Animal training has endurance. Basically, the drug sends a signal to the muscle and tells it to modify it
Half of the mice studied showed improved run endurance in terms of time and distance. Obviously, a small drug-like molecule can increase the metabolic rate of skeletal muscle, increase exercise tolerance
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